Sue, Cheryl and Lexi are best friends. They do something special every year for their birthday as they were all born on the same day. Now their 18th birthday, they set out to lose their virginity.

Three college students get lost in the seedy streets where they encounter a crazed gang of homeless derelicts that seizes them and one-by-one, horrifically kills all but one man. The surviving man escapes on foot, naked and unarmed, with a pack of depraved transients in pursuit, and only seconds away from capture.